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The human body responds the same way in a high altitude room as it would in mountainous areas with the same (simulated) heigth. One of the first reactions the body will show is an increase in heart rate and rapid breathing to make up for the lack of oxygen. 

At the same time, the production of red blood cells is stimulated, which will eventually lead to acclimatization. Similar as in the mountains, people could get altitude sickness. This can be prevented by starting at a low level and increasing the height step-by-step (as described in our user manuals). 

When you are uncertain regarding your health, please advice your doctor before using high altitude training techniques.